My work focuses on U.S. and Mexico negotiations regarding the shared waters of the Colorado River and the shared hydrocarbons resources in the Gulf of Mexico. Resource management decisions about open, evolving, and interconnected water, energy, and environmental networks are complex. When multiple stakeholders from different countries with competing interests and values are involved, the challenges are compounded. The doctoral research aims to highlight the negotiation, decision-making, leadership, and communication strategies that can alter the prospects to find agreement. The focus is on how government, corporate, and non-profit are building new partnerships to defy the odds, create value, enhance trust, and deliver effective results.